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MYP_153995
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Basic Information
Q53 CecB
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C177H303N53O43S
Standard
Sequence
RWKIFKKIEKMGRNIRDGIVKAGPAIQVLGSAKAI
Physicochemical Analysis
3893.69 Da
11.17
6.76
6.54
0.1931
-0.13
0.91
-0.04
52.56
106.00
0.0571
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1582.55
-11.62
56.0
51.0
138.0
274.0
4.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005704 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 700565
8 μM
MIC
PMID31045339 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31045339/
RECORD: Rec_0015485 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
0.15 μM
MIC
PMID31045339 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31045339/
RECORD: Rec_0028417 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Cytotoxic
②The cell viability of CCD cells induced by CecB Q53 is 108
PMID31045339 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31045339/
RECORD: Rec_0056011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Staphylococcus aureus ATCC BAA-44
20 μM
MIC
PMID31045339 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31045339/
RECORD: Rec_0100297 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells
PMID31045339 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31045339/
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