Peptide Database

Peptide NameiAβ5p

Function Ontology

beta-sheet breaker peptides

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC33H43N5O8

DescriptionStandard

        LPFFD
    

Molecular Weight637.72 Da

Isoelectric Point (pI)4.30

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.2471

GRAVY Index0.86

Hydrophobic Moment 0.38

Boman Index0.53

Instability Index109.72

Aliphatic Index 78.00

Aromaticity 0.4000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 208.23

LogP 0.85

H-bond Donors 6.0

H-bond Acceptors 7.0

Rotatable Bonds 16.0

Heavy Atoms 46.0

Ring Count 3.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120016 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAmyloid-beta

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

beta-sheet breaker peptides

MethodRP-HPLC

Half-LifeHuman plasma, in vitro; >86400 s

RECORD: Rec_0330790 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAmyloid-beta

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

beta-sheet breaker peptides

MethodRP-HPLC

Half-LifeRat brain homogenate, in vitro; <60 s