Peptide Database

Peptide NameNeurotoxin Hm-1

Function Ontology

Anticancer

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC185H274N48O49S7

DescriptionStandard

        GCIPYGKTCEFWSGPWCCAGKCKLNVWSMTLSCTRNF
    

Molecular Weight4178.90 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0730

GRAVY Index0.02

Hydrophobic Moment 0.36

Boman Index0.13

Instability Index15.11

Aliphatic Index 42.16

Aromaticity 0.1622

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1545.76

LogP -14.47

H-bond Donors 61.0

H-bond Acceptors 59.0

Rotatable Bonds 128.0

Heavy Atoms 289.0

Ring Count 11.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186197 VERIFIED: NO

Provenance & Taxonomy

OrganismHeriaeus melloteei [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-18; 9-22; 17-33

Bio-Activity Profile

Function

Toxin

TargetNav1

RECORD: Rec_0325489 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer