Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2353H3802N616O644S17

DescriptionStandard

        MVCLWCVLVLLTLLPASQSTAGVKVRLTQKALEYGRQIGITVLQQKLKTITVPDFSGSTRVRPIGKVRFSFTRMRIVSLGLPKSAVGLVPGTSVKFSIRNAFIKMQGNWRVKYLFIRDSGSFDLSVNDLTITTSIAILRDATGRPAVNSAGCSATVGSAKVKFRGGASWLYNLFRSSAGKAIRKALEKKICPLVAKTIPDMNPRLKTLNVLAKVDKYAEIEYSMVASPVISKESIDLSLKGEFYNIGQHREPPFSPTPFSLPLQNSNMLYIGLSAFTVNSAAFVYHTAGALSLYITDDMIPSNIPIRLNTRTFGTFIPQIAKMYPGLMMKLHMKTAKVPIITFQPNNVTVQASSTVTAYAIQPSATLSPLFVLNLDASVSARIYVTGLKVAGSLTLNSFEMTLGKSYVGLFQVKPLDTIFATVLRWAVLPIVNVNLRKGYPLPAVGKMNLINPKLQVLQDYALIGTDLKFTG
    

Molecular Weight51570.20 Da

Isoelectric Point (pI)10.13

Net Charge (pH 7.0)31.71

Net Charge (pH 7.4) 31.19

Charge Density (pH 7.0) 0.0672

GRAVY Index0.24

Hydrophobic Moment 0.72

Boman Index0.15

Instability Index32.32

Aliphatic Index 104.92

Aromaticity 0.0869

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179926 VERIFIED: NO

Provenance & Taxonomy

OrganismChanos chanos (Milkfish) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria