Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length400 amino acids

Chemical FormulaC1998H3114N576O594S10

DescriptionStandard

        MGIYQAVPQTDPVTDTEAPQRAQTAKKKKLVAPEDIPKPKKRSALWKWWNGHHEEMDYQRAVEEAERAQRARAAIAGASVLRPVAGNFAIRGTWAVVGEAATGVAGLPLAAFLIGMMPGRLNDGEQDFIDRMRAEQAREVPTRVRFTWETNSRGNPVPHGWHTPPGQDRVRVRRMEWDDRRKAYTFTTEEDPRITLIWTPDNPGIDVPNHTGNQYPPVLPNPVMVDPLPDDTGLHATTSPAPEERDFADYILILPFPDIPPIYIYLSKPPVEFLEVELYSDFKRRSRQGKYEADHMPSAAAVRAYFKRLHPDLDDEDLDAYAQDVAAIVIPKEVHQKMSETYGGRNTPAQIDLDSRNLRAAADRNLDAIKPALKEHGATEGQIEAARTKLHELNSKMGLY
    

Molecular Weight45028.25 Da

Isoelectric Point (pI)5.93

Net Charge (pH 7.0)-6.46

Net Charge (pH 7.4) -7.35

Charge Density (pH 7.0) -0.0161

GRAVY Index-0.66

Hydrophobic Moment 0.77

Boman Index-0.10

Instability Index42.73

Aliphatic Index 72.78

Aromaticity 0.0775

Extinction Coeff. Reduced 63370.00

Extinction Coeff. Oxidized 63370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354431 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli