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MYP_153926
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Basic Information
Magainin-MW1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C112H177N29O28S
Standard
Sequence
GIGKFLHSAGKFGKAFLGEVMKS
Physicochemical Analysis
2409.85 Da
10.00
2.85
2.59
0.1237
0.19
0.64
0.21
-8.48
72.17
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
914.04
-7.13
32.0
33.0
84.0
170.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043721 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
200 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/21664395/ PMID21664395 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21664395/
RECORD: Rec_0128570 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
100 μM
MIC
PaperPeptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific
RECORD: Rec_0145863 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part C 152 (2010) 467-472. Antimicrobial peptides with therapeutic potential from skin secretions of the Marsabit clawed frog Xenopus borealis (Pipidae)
RECORD: Rec_0163347 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
200 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20656059/ PMID20656059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20656059/
RECORD: Rec_0169907 VERIFIED: NO
Provenance & Taxonomy
Xenopus borealis [Animal] [Animal]; Xenopus muelleri [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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