Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC224H349N65O73S6

DescriptionStandard

        HSGDAQGPDSCNHRGGLCRVGTCVSGEYPAQYCFEPIILCCKNLLPATTE
    

Molecular Weight5312.95 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-2.11

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0422

GRAVY Index-0.22

Hydrophobic Moment 0.43

Boman Index0.05

Instability Index37.09

Aliphatic Index 64.40

Aromaticity 0.0600

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2181.94

LogP -27.13

H-bond Donors 79.0

H-bond Acceptors 79.0

Rotatable Bonds 166.0

Heavy Atoms 368.0

Ring Count 9.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270220 VERIFIED: YES

Provenance & Taxonomy

OrganismParus major [Animal]

FamilyDefensin

Tax ID9157

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/