Peptide Database

Peptide Name[Tyr21,Gly24]-somatostatin-28

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC342H536N98O113S5

DescriptionStandard

        SAGLLTQEWSAVEDLLAQMSLPEADAQRDAEMVSTATGGGRMNQESIEPPNNLPPRERKAGCKNFYWKGFTSC
    

Molecular Weight7988.83 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0485

GRAVY Index-0.65

Hydrophobic Moment 0.42

Boman Index-0.07

Instability Index48.21

Aliphatic Index 56.30

Aromaticity 0.0685

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3412.06

LogP -40.62

H-bond Donors 117.0

H-bond Acceptors 115.0

Rotatable Bonds 262.0

Heavy Atoms 558.0

Ring Count 12.0

Amide Bonds 80.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0177111 VERIFIED: YES

Provenance & Taxonomy

OrganismPlatichthys flesus [Animal]

Familysomatostatin

Tax ID8260

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide62-73

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour