Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC788H1271N215O212S16

DescriptionStandard

        MLLAYRPTFLCTSFCFIAHDPPPEPRPMKINKNLSPESHCRMFWTPGSATFFLKTMKLLLLTLTVCLILFQILPVCRGQKSCWIIKGHCRKNCKSGEQVKKPCKNGDYCCILSKTDSQPHRLTQAPTGKSQILSTDLEGNDVLEHVPLVIMRQGKI
    

Molecular Weight17661.87 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)10.83

Net Charge (pH 7.4) 10.17

Charge Density (pH 7.0) 0.0694

GRAVY Index-0.11

Hydrophobic Moment 0.57

Boman Index0.03

Instability Index35.44

Aliphatic Index 86.22

Aromaticity 0.0705

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6787.48

LogP -59.91

H-bond Donors 242.0

H-bond Acceptors 244.0

Rotatable Bonds 581.0

Heavy Atoms 1231.0

Ring Count 31.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359048 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal