Peptide Database

Peptide NameS-type pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length581 amino acids

Chemical FormulaC2785H4448N806O841S15

DescriptionStandard

        MEHKWEVKYDPYNYNNGVPPEPGLYWQNGSWNWENGEETLTVTSIPIPGLDEKVKECLANNICFICGKKNCPYIKNDKHYRELLDACRRGDGATAKRIYMQRLAPFLHVFSGQRNEGLQRELNAQARAKAEAEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKALFDKAGVKPAPVYTPAMVAEANKALKAPGAMVLNQTPGTAQMALAGAGVWTAAGDVAGSITNWFSNALSKLSVPAVSPGLLKASMATLWFHSKPAGQGSDQVPGRDVPALFAFPARALADAKAIEAGMKTVNMPARGSLMKSNGQLALQLLKTGNGGIPAAVQVLTGVRDPKTGLDRITVPAIAGAGVPARTILINPAQPPSAPSNTGTPPPPVPVTPVHTGTEVKPVDTITVTTTPVADHNGLQDFIYWRPDAAGTGVEPVYVVLSDPLDSGRFTRKQLDRKYKHAGDFGVSDTKKNRETLTKFRDAIEAHLADKETVEKGTYRREKGSKVYFNPKTMRVVVLKPNGDFLSGWKINPDAENGKIYLETGDL
    

Molecular Weight63158.98 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)12.25

Net Charge (pH 7.4) 11.36

Charge Density (pH 7.0) 0.0211

GRAVY Index-0.57

Hydrophobic Moment 0.79

Boman Index-0.08

Instability Index33.66

Aliphatic Index 71.34

Aromaticity 0.0637

Extinction Coeff. Reduced 70360.00

Extinction Coeff. Oxidized 70610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069174 VERIFIED: YES

Provenance & Taxonomy

OrganismSerratia marcescens [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)