Peptide Database

Peptide NamePeptide 12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC49H76N14O10

DescriptionStandard

        PWRLSLHL
    

Molecular Weight1021.22 Da

Isoelectric Point (pI)10.18

Net Charge (pH 7.0)1.05

Net Charge (pH 7.4) 0.94

Charge Density (pH 7.0) 0.1307

GRAVY Index0.05

Hydrophobic Moment 0.42

Boman Index0.12

Instability Index5.15

Aliphatic Index 146.25

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 379.63

LogP -0.70

H-bond Donors 15.0

H-bond Acceptors 12.0

Rotatable Bonds 30.0

Heavy Atoms 73.0

Ring Count 4.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405494 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus epidermidis ATCC 12228

Activity8 μM

MethodMIC

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