Peptide Database

Peptide NameBeta-defensin 37

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC325H518N88O84S9

DescriptionStandard

        MKISCFLLLVLSLSCFQINPFAVLDTRVCIEKRNTCHILQCPRFRDVVGTCYEGKGKCCHKYF
    

Molecular Weight7290.71 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.60

Net Charge (pH 7.4) 4.15

Charge Density (pH 7.0) 0.0730

GRAVY Index0.32

Hydrophobic Moment 0.52

Boman Index0.07

Instability Index53.86

Aliphatic Index 92.70

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2768.40

LogP -21.82

H-bond Donors 105.0

H-bond Acceptors 100.0

Rotatable Bonds 241.0

Heavy Atoms 506.0

Ring Count 11.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0080786 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence