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MYP_153786
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Basic Information
Flower-specific gamma-thionin, ZmD32
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
47 amino acids
C220H356N88O61S8
Standard
Sequence
RTCQSQSHRFRGPCLRRSNCANVCRTEGFPGGRCRGFRRRCFCTTHC
Physicochemical Analysis
5466.25 Da
11.03
9.86
9.44
0.2097
-0.91
0.46
-0.44
97.01
16.60
0.0851
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2473.87
-36.53
101.0
81.0
178.0
377.0
8.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0217572 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
Thionin
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human histiocytic lymphoma U-937 90-100% Killing
50 μM
PMID31031739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31031739/
RECORD: Rec_0219494 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
Thionin
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human dermal fibroblasts
30 % killing at 50 μM
Cytotoxicity
PMID31031739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31031739/
RECORD: Rec_0224556 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
Thionin
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa PAO1
1.7
IC50
PMID31031739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31031739/
RECORD: Rec_0229692 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. tropicalis ATCC 750
0.5 μM
IC50
PaperSalt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32
RECORD: Rec_0229723 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
Thionin
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida krusei
0.9
IC50
PMID31031739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31031739/
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