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MYP_153756
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Basic Information
SK-24
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
24 amino acids
C134H230N40O34
Standard
Sequence
SKEKIGKEFKRIVQRIKDFLRNLV
Physicochemical Analysis
2945.51 Da
10.55
4.46
4.24
0.1859
-0.69
0.97
-0.33
12.78
105.42
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1266.73
-9.02
45.0
39.0
109.0
208.0
2.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0238553 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. faecium V284-17
2 μM
MIC
PMID34959645 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34959645/
RECORD: Rec_0241622 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
K-pneumoniae E406-17
>32 μM
MIC
PaperStructure and Activity of a Selective Antibiofilm Peptide SK-24 Derived from the NMR Structure of Human Cathelicidin LL-37.
RECORD: Rec_0274988 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human RBC
200 μM
Hemolysis
PMID34959645 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34959645/
RECORD: Rec_0294199 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa E411-17
32 μM
MIC
PMID34959645 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34959645/
RECORD: Rec_0296393 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus USA300
4 μM
MIC
PaperStructure and Activity of a Selective Antibiofilm Peptide SK-24 Derived from the NMR Structure of Human Cathelicidin LL-37.
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