Peptide Database

Peptide NameSLAY-screened peptide P4411

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC106H184N28O27S

DescriptionStandard

        VFLVVLIISTGVLPTRTIRCN
    

Molecular Weight2314.83 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)1.72

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0821

GRAVY Index1.41

Hydrophobic Moment 0.42

Boman Index0.36

Instability Index14.65

Aliphatic Index 166.67

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 884.34

LogP -6.16

H-bond Donors 33.0

H-bond Acceptors 30.0

Rotatable Bonds 73.0

Heavy Atoms 162.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281624 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/