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MYP_153630
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Basic Information
Cathelicidin-PY
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C151H263N47O39S2
Standard
Sequence
RKCNFLCKLKEKLRTVITSHIDKVLRPQG
Physicochemical Analysis
3425.13 Da
10.20
5.83
5.53
0.2009
-0.48
0.73
-0.26
31.55
100.69
0.0345
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1435.28
-12.56
53.0
48.0
121.0
239.0
3.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000698 VERIFIED: YES
Provenance & Taxonomy
Paa yunnanensis [Animal]
Cathelicidin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory Anticancer
Escherichia coli 08A852 CI/DR
1.37 μM
MIC
PaperStructure and Function of A Potent Lipopolysaccharide-binding Antimicrobial and Anti-inflammatory Peptide
RECORD: Rec_0018427 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeiana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial
PaperPDB 2LR7 structural record; NMR; chain A; residues 1-29
RECORD: Rec_0022573 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
50 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/23594231/ PMID23594231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23594231/
RECORD: Rec_0047802 VERIFIED: YES
Provenance & Taxonomy
Paa yunnanensis [Animal]
Cathelicidin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory Anticancer
Pseudomonas aeruginosa 08031205
9.38 μM
MIC
PaperStructure and Function of A Potent Lipopolysaccharide-binding Antimicrobial and Anti-inflammatory Peptide
RECORD: Rec_0052237 VERIFIED: YES
Provenance & Taxonomy
Paa yunnanensis [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-inflammatory Hemolytic
PMID23594231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23594231/
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