Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length364 amino acids

Chemical FormulaC1863H2925N487O522S7

DescriptionStandard

        TNPGFVVRITQAGLDYAQEQAIATLEKKLAQLKLPDISGDSRVLRVGKVHYELSRLRLRDFHLPYSRITPISNKGLQVSISNAFAELDGDWRVKFLFVRDHGSFDLRVENIYIKVLLRLGSDTTGKPTISTPDCSAHISKVRVLFSGKLGWLYNLFHSVIERRLRKILEDKVCDKVAMSVYNELQTYIRTLPVTARIDDKIGIDYSLVAPPRATPKSLDADLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKDVEFKLNTSVFSAFIPQLEEKYPNMPMKFRVSTPTAPFLTVGEGGISFQPIVDVQAYAILPSSRLAPLFLLSLVSSDTA
    

Molecular Weight40721.56 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)6.11

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.0168

GRAVY Index-0.01

Hydrophobic Moment 0.83

Boman Index0.07

Instability Index38.33

Aliphatic Index 98.30

Aromaticity 0.1044

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229593 VERIFIED: NO

Provenance & Taxonomy

OrganismMelospiza melodia (Song sparrow) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria