Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC787H1187N177O244S7

DescriptionStandard

        QGIVYPSGNYSALPFVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSVIPEVAQYSVTPYPVMLKLTAIETPIVSLQQDSFTLEIQGSMEVFAVLPDSSTQSLFTMSITANTSITVNTFDQKLMGSLCLNR
    

Molecular Weight17256.34 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.24

Net Charge (pH 7.4) -10.51

Charge Density (pH 7.0) -0.0652

GRAVY Index0.31

Hydrophobic Moment 0.48

Boman Index0.26

Instability Index49.97

Aliphatic Index 85.73

Aromaticity 0.1401

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6679.35

LogP -66.01

H-bond Donors 229.0

H-bond Acceptors 241.0

Rotatable Bonds 544.0

Heavy Atoms 1215.0

Ring Count 31.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198642 VERIFIED: NO

Provenance & Taxonomy

OrganismEudromia elegans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria