Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC423H695N115O119S

DescriptionStandard

        MIPQLSRLYPDKELELEVSPESAPFLVFTPGNVVLVPVINIQAFVLLPTSSERRPLFQLRARTNIIATIRVSSNKIQGSVTPGR
    

Molecular Weight9327.81 Da

Isoelectric Point (pI)10.23

Net Charge (pH 7.0)2.51

Net Charge (pH 7.4) 2.28

Charge Density (pH 7.0) 0.0299

GRAVY Index0.15

Hydrophobic Moment 0.57

Boman Index0.08

Instability Index61.48

Aliphatic Index 114.76

Aromaticity 0.0595

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3736.59

LogP -34.17

H-bond Donors 127.0

H-bond Acceptors 123.0

Rotatable Bonds 300.0

Heavy Atoms 658.0

Ring Count 14.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250908 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllostomus discolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria