Peptide Database

Peptide NameLipotropin beta

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC387H607N113O113S2

DescriptionStandard

        ELATNEVNHPQEDSALIQQKKKDGSYKMKHFRWSSPPAGKRYGGFMKSWDERSQKPLLTLFKNVINKEHQKKDQ
    

Molecular Weight8714.78 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)6.10

Net Charge (pH 7.4) 5.75

Charge Density (pH 7.0) 0.0824

GRAVY Index-1.36

Hydrophobic Moment 0.60

Boman Index-0.30

Instability Index55.38

Aliphatic Index 48.78

Aromaticity 0.0946

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3736.92

LogP -38.12

H-bond Donors 126.0

H-bond Acceptors 124.0

Rotatable Bonds 302.0

Heavy Atoms 615.0

Ring Count 16.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278946 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyPOMC

Tax ID7962

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0379624 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0399909 VERIFIED: YES

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyLipotropin

Tax ID7962

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour