Peptide Database

Peptide NameDermaseptin-B6 (DRS-B6) (Dermaseptin BVI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC363H587N95O120S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSVCEEEKRENEDEMEQEDDEQSEEKRALWKDILKNAGKAALNEINQLVNQGEL
    

Molecular Weight8298.30 Da

Isoelectric Point (pI)4.42

Net Charge (pH 7.0)-8.48

Net Charge (pH 7.4) -8.74

Charge Density (pH 7.0) -0.1177

GRAVY Index-0.52

Hydrophobic Moment 0.69

Boman Index-0.09

Instability Index58.33

Aliphatic Index 98.89

Aromaticity 0.0556

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3553.98

LogP -31.05

H-bond Donors 118.0

H-bond Acceptors 115.0

Rotatable Bonds 299.0

Heavy Atoms 581.0

Ring Count 5.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072398 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria