Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC378H603N111O117S12

DescriptionStandard

        MKTFPVAVAVAVVLTFICVQQSSAVPVREPGEPMSVDNPAADHEETDDAGEMPYNNREKRGVRCKFCCNCCTRGVCGLCCRF
    

Molecular Weight8959.28 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0181

GRAVY Index-0.07

Hydrophobic Moment 0.53

Boman Index-0.02

Instability Index52.71

Aliphatic Index 61.71

Aromaticity 0.0610

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3639.20

LogP -41.55

H-bond Donors 132.0

H-bond Acceptors 129.0

Rotatable Bonds 287.0

Heavy Atoms 618.0

Ring Count 12.0

Amide Bonds 87.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0408337 VERIFIED: NO

Provenance & Taxonomy

OrganismCyclopterus lumpus [Animal]

FamilyHepcidin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial