Peptide Database

Peptide NameCrotamine

Function Ontology

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Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC156H246N46O40S6

DescriptionStandard

        HCSPKEKICLPPSSDFGKMDCRWRWKCCKK
    

Molecular Weight3598.30 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.46

Charge Density (pH 7.0) 0.1599

GRAVY Index-1.00

Hydrophobic Moment 0.45

Boman Index-0.31

Instability Index97.29

Aliphatic Index 26.00

Aromaticity 0.1000

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1393.62

LogP -12.15

H-bond Donors 54.0

H-bond Acceptors 52.0

Rotatable Bonds 118.0

Heavy Atoms 248.0

Ring Count 9.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246098 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus durissus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)