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MYP_153461
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Basic Information
Satanin 1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
38 amino acids
C198H344N60O49
Standard
Sequence
RSKKWRKIEKRVKKIFEKTKEALPVIQGVATIVGAVGR
Physicochemical Analysis
4349.22 Da
11.17
8.76
8.54
0.2305
-0.48
0.87
-0.21
37.42
97.37
0.0526
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1818.46
-14.03
66.0
58.0
156.0
307.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0377390 VERIFIED: YES
Provenance & Taxonomy
Dichotomius satanas [Animal]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-inflammatory
LPS-stimulated human peripheral blood mononuclear cells
TNF-α production modulation assay
PaperHenao Arias DC et al. Novel antimicrobial cecropins derived from O. curvicornis and D. satanas dung beetles. Peptides. 2021;145:170626. doi:10.1016/j.peptides.2021.170626. PMID:34391826 PMID34391826 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34391826/
RECORD: Rec_0380712 VERIFIED: YES
Provenance & Taxonomy
Dichotomius satanas [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae ATCC BAA 170513
3.12 μg/mL
MIC
PaperNovel antimicrobial cecropins derived from O. curvicornis and D. satanas dung beetles. PMID34391826
RECORD: Rec_0381659 VERIFIED: NO
Provenance & Taxonomy
Dichotomius satanas [Animal]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PaperHenao Arias DC et al. Novel antimicrobial cecropins derived from O. curvicornis and D. satanas dung beetles. Peptides. 2021;145:170626. doi:10.1016/j.peptides.2021.170626. PMID:34391826 PMID34391826 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34391826/
RECORD: Rec_0432506 VERIFIED: YES
Provenance & Taxonomy
Dichotomius satanas [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
187.5 μg/mL
HC50 / Hemolysis
PaperHenao Arias DC et al. Novel antimicrobial cecropins derived from O. curvicornis and D. satanas dung beetles. Peptides. 2021;145:170626. doi:10.1016/j.peptides.2021.170626. PMID:34391826 PMID34391826
RECORD: Rec_0432507 VERIFIED: YES
Provenance & Taxonomy
Dichotomius satanas [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal Antimicrobial
Malassezia furfur CBS 1878
25 μg/mL
MIC (modified CLSI M27-A3 broth microdilution; >90% growth inhibition; 72 h at 33 °C)
PaperMolina Pineda JS, Gómez Rivera MA, Ehemann Guerrero K, et al. Evaluation of Satanin 1 as a potential antifungal antimicrobial peptide to treat Malassezia infections. Scientific Reports. 2025;15:14898. doi:10.1038/s41598-025-99464-0. PMID:40295684 PMID40295684
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