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MYP_153449
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Basic Information
Human cJun (252-279)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C150H281N63O38S2
Standard
Sequence
RIKAERKRMRNRIAASKSRKRKLERIARGC
Physicochemical Analysis
3639.37 Da
12.00
11.75
11.52
0.3917
-1.45
0.84
-0.79
30.93
65.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1752.57
-20.36
69.0
52.0
137.0
253.0
0.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070894 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0171847 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Protein-derived CPP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide
RAW 264.7
Fluorescence-based uptake assay
PMID11084031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11084031/
RECORD: Rec_0173843 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0187623 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Protein-derived CPP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Fluorophore labeling
C-term detail: Alexa 488 labeling at glycyl cysteine sequence
Bio-Activity Profile
Cell-penetrating peptide
CHO-K1; HeLa; Jurkat
Fluorescence-based uptake assay
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0199308 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Fluorescein labeling
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
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