Peptide Database

Peptide NameDefensin; alpha; 40

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC449H729N129O147S9

DescriptionStandard

        MKTLVLLSALFLLAFQVQADPIQKTDEETNTEVQPEEEEQAMSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL
    

Molecular Weight10574.95 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-4.44

Net Charge (pH 7.4) -4.83

Charge Density (pH 7.0) -0.0478

GRAVY Index-0.49

Hydrophobic Moment 0.61

Boman Index-0.12

Instability Index58.86

Aliphatic Index 75.48

Aromaticity 0.0538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4510.74

LogP -49.30

H-bond Donors 161.0

H-bond Acceptors 153.0

Rotatable Bonds 362.0

Heavy Atoms 734.0

Ring Count 9.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268872 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic