Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC350H545N103O102S5

DescriptionStandard

        QHWSYGLSPGGKRDLDSLSDTLGNIIERFPHVDSPCSVLGCVEEPHVPRMYRMKGFIGSERDIGHRMYKK
    

Molecular Weight7988.03 Da

Isoelectric Point (pI)8.03

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.64

Charge Density (pH 7.0) 0.0157

GRAVY Index-0.66

Hydrophobic Moment 0.68

Boman Index-0.10

Instability Index54.11

Aliphatic Index 66.71

Aromaticity 0.0857

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3277.67

LogP -32.10

H-bond Donors 117.0

H-bond Acceptors 112.0

Rotatable Bonds 262.0

Heavy Atoms 560.0

Ring Count 16.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101211 VERIFIED: YES

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyProgonadoliberin

Tax ID8175

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour