Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC480H727N133O136S9

DescriptionStandard

        MKILLFFCILLFFGVLIPPARSEGHHITFSRWKSCTAIGGRCKNQCDDSEFRISYCARPTTHCCVTECDPTDPNNWIPKDSVGTQEWYPKDSRH
    

Molecular Weight10825.30 Da

Isoelectric Point (pI)7.57

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.22

Charge Density (pH 7.0) 0.0083

GRAVY Index-0.36

Hydrophobic Moment 0.42

Boman Index-0.02

Instability Index65.58

Aliphatic Index 62.23

Aromaticity 0.1170

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4283.81

LogP -41.35

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 342.0

Heavy Atoms 758.0

Ring Count 25.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141188 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence