Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC930H1411N207O280S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFHPFIDLDLKGIVYPTGNYTGPPYLAAPIILPDQSNSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20227.89 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.15

Net Charge (pH 7.4) -14.48

Charge Density (pH 7.0) -0.0773

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index42.66

Aliphatic Index 99.18

Aromaticity 0.1311

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7673.64

LogP -79.83

H-bond Donors 259.0

H-bond Acceptors 275.0

Rotatable Bonds 640.0

Heavy Atoms 1425.0

Ring Count 37.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267422 VERIFIED: NO

Provenance & Taxonomy

OrganismPodilymbus podiceps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria