Peptide Database

Peptide NameExtended FMRFamide-12

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC73H114N22O26

DescriptionStandard

        SPVPEDDRGDNFVRL
    

Molecular Weight1715.82 Da

Isoelectric Point (pI)4.23

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.74

Charge Density (pH 7.0) -0.1689

GRAVY Index-1.06

Hydrophobic Moment 0.45

Boman Index-0.29

Instability Index68.03

Aliphatic Index 64.67

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 789.46

LogP -8.89

H-bond Donors 26.0

H-bond Acceptors 24.0

Rotatable Bonds 53.0

Heavy Atoms 121.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125276 VERIFIED: YES

Provenance & Taxonomy

OrganismTyrannophasma gladiator [Animal]

FamilyExtended FMRFamide

Tax ID270861

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0246996 VERIFIED: YES

Provenance & Taxonomy

OrganismTyrannophasma gladiator [Animal]

FamilyFMRFamide related peptide

Tax ID270861

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0312318 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/