Peptide Database

Peptide NameAla48 substitution mutant of pAntp (43-58)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC96H163N33O20S

DescriptionStandard

        RQIKIAFQNRRMKWKK
    

Molecular Weight2131.60 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.4223

GRAVY Index-1.56

Hydrophobic Moment 0.36

Boman Index-0.63

Instability Index46.60

Aliphatic Index 55.00

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 934.66

LogP -6.79

H-bond Donors 34.0

H-bond Acceptors 28.0

Rotatable Bonds 78.0

Heavy Atoms 150.0

Ring Count 3.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413711 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyPenetratin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

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