Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2337H3675N599O645S18

DescriptionStandard

        TDPGFVAMISQKGLDFACQQGVVELQKELQAISVPDFSGVFKIKHLGKGSYEFYSMAVDGFHIPNPKIEMLPSDGLRVFIKDASIKINGKWMSRKNFLKAGGNFELSIQGVSISTDLILGSDSSGHITTICSNCDSHIDSVHIKISGSMLGWLIRLFHRKIETSLKNIIYKKICKIVRDSVSSKLQPYLKTLSVITRVDDVTSVDYSLLAPLTTTNQFLEGQLKGEFFWRGHRDPLPIHPPVMRFVPNGAYMVCMGISDYFFNTEVLAYQQSGTLKMTLGGQLLSNNGRFQLNTDFLRTFLPKVAKMFPSMGVQLLISAPVPVHLSIQPSGLSFNPKLETQAFVVLPNASLVPLFVLGMKTNASLEVDAEENRLVGEMKLGSRWLLELKESKFGPFKVEYLEDVINYLVSTLVLPKINERLRRGFPLPLPAGIRFSHFTFYPYQNFLLLEADLHLI
    

Molecular Weight51059.97 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)7.34

Net Charge (pH 7.4) 6.41

Charge Density (pH 7.0) 0.0161

GRAVY Index0.08

Hydrophobic Moment 0.86

Boman Index0.13

Instability Index36.92

Aliphatic Index 100.83

Aromaticity 0.1009

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0183722 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

RECORD: Rec_0196225 VERIFIED: YES