Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC438H716N130O142S8

DescriptionStandard

        MRTLTLLTAVLLLALQAQAGPLQARCDEAAGQEQRGVNDQDISISFAWDKSSALQVSGSTRALACTCRLVYCQQGERRAGSCIIGGVGFTYCCSLED
    

Molecular Weight10331.68 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-1.55

Net Charge (pH 7.4) -1.89

Charge Density (pH 7.0) -0.0160

GRAVY Index0.10

Hydrophobic Moment 0.61

Boman Index0.05

Instability Index45.79

Aliphatic Index 91.65

Aromaticity 0.0515

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4413.52

LogP -53.96

H-bond Donors 162.0

H-bond Acceptors 149.0

Rotatable Bonds 346.0

Heavy Atoms 718.0

Ring Count 7.0

Amide Bonds 106.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0264763 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence