Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length126 amino acids

Chemical FormulaC656H1012N172O186S11

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKFPAAGWFVERCWKNDIGYCRKRCLLLERYKLLCVNKQSCCIPLRSYDPYTQWPIHRTFFKDLNVEYITHDDFPFSPDSGFTDEVTVKATMTQESRVTGATASQRDSS
    

Molecular Weight14636.81 Da

Isoelectric Point (pI)8.17

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0128

GRAVY Index-0.17

Hydrophobic Moment 0.59

Boman Index0.01

Instability Index46.00

Aliphatic Index 75.79

Aromaticity 0.1270

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5765.52

LogP -50.78

H-bond Donors 210.0

H-bond Acceptors 201.0

Rotatable Bonds 474.0

Heavy Atoms 1025.0

Ring Count 27.0

Amide Bonds 133.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371377 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence