Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC729H1152N214O212S7

DescriptionStandard

        MAKVQFKQRNETTLLIVHCAATPPSMNIGLREIRQWHKEKGWLDVGYHFIIRRDGTIEDGRDVGAVGAHCEGKNYTSVGVCLVGGVDASGKPQANFTPQQMQSLRDVLAGLKVEYPDATIHGHREFAAKACPSFDVQRWLKTNELVTAK
    

Molecular Weight16530.71 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)3.00

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.0201

GRAVY Index-0.37

Hydrophobic Moment 0.75

Boman Index-0.02

Instability Index40.42

Aliphatic Index 78.52

Aromaticity 0.0738

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6855.01

LogP -69.14

H-bond Donors 240.0

H-bond Acceptors 228.0

Rotatable Bonds 549.0

Heavy Atoms 1162.0

Ring Count 26.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138337 VERIFIED: YES

Provenance & Taxonomy

OrganismErwinia phage vB_EamP-L1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic