Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC411H639N119O114S

DescriptionStandard

        MSQYPELIAQFSSGNQTRIKQGLTAKAPLEGWHYGPKEIVKKFQIHHRVAIEYGGSVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight9103.26 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0377

GRAVY Index-0.64

Hydrophobic Moment 0.54

Boman Index-0.08

Instability Index58.82

Aliphatic Index 85.00

Aromaticity 0.1026

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 12950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3772.34

LogP -32.46

H-bond Donors 131.0

H-bond Acceptors 123.0

Rotatable Bonds 301.0

Heavy Atoms 645.0

Ring Count 18.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113287 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Pyocin

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal

RECORD: Rec_0371652 VERIFIED: NO