Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC361H605N101O98S7

DescriptionStandard

        MKLLLVLTVTLLLARVTPATKCWGKLGNCRTTCEENEIFHILCGTEAKCCVNPKYVPVKTKFRTRKQGLNSAV
    

Molecular Weight8152.74 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.1032

GRAVY Index0.09

Hydrophobic Moment 0.50

Boman Index0.02

Instability Index30.88

Aliphatic Index 97.40

Aromaticity 0.0548

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3219.56

LogP -29.24

H-bond Donors 119.0

H-bond Acceptors 114.0

Rotatable Bonds 273.0

Heavy Atoms 567.0

Ring Count 9.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177821 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence