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MYP_153112
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Basic Information
EA8_2H2W
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
26 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XACSHSGWGCGHGSWSCGRRRRRRRR
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0268680 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical/noncanonical residue peptide [Modified]
FITC
Amidation
X=Ahx (6-aminohexanoic acid) at position 1
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperExploration of the design principles of a cell-penetrating bicylic peptide scaffold. Bioconjug Chem. 2014 May 21;25(5):955-964. doi: 10.1021/bc500107f. PMID: 24697151. PMID24697151 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24697151/
RECORD: Rec_0397305 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical/noncanonical residue peptide [Modified]
FITC
Amidation
X=Ahx (6-aminohexanoic acid) at position 1
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperExploration of the design principles of a cell-penetrating bicylic peptide scaffold. Bioconjug Chem. 2014 May 21;25(5):955-964. doi: 10.1021/bc500107f. PMID: 24697151. PMID24697151 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24697151/