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MYP_153055
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Basic Information
Unnamed
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C7H12N2O5
Standard
Sequence
AD
Physicochemical Analysis
204.18 Da
4.30
-1.20
-1.39
-0.5999
-0.85
0.59
-0.14
-37.45
50.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-1.62
4.0
4.0
5.0
14.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0234803 VERIFIED: YES
Provenance & Taxonomy
Trachipteridae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV-2
PMID34877713 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34877713/
RECORD: Rec_0335728 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperQuantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity. PMID17117396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17117396/
RECORD: Rec_0359832 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Model sensory peptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
0.17 Rcaf
Relative bitterness (Rcaf)
PaperSynthesis of bitter peptides composed of aspartic acid and glutamic acid. Agric. Biol. Chem., 52, 871-872, 1988
RECORD: Rec_0420922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
>1600 μM
IC50
Rat plasma, in vitro; 3840 s
PMID14980787 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14980787/
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