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MYP_153053
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Basic Information
NZ16K
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
40 amino acids
C191H285N55O54S6
Standard
Sequence
GFGCNGPWNEDDLRCKNHCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4408.03 Da
8.84
3.78
3.43
0.0946
-0.69
0.44
-0.08
11.42
29.25
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1774.01
-19.30
67.0
65.0
145.0
306.0
9.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0268520 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 25923
0.014 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0277219 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. pneumoniae CVCC2350
0.227 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0290729 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. suis CVCC3309 or CVCC3928 or CVCC606
0.007-0.014 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0302067 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923 or ATCC 6538 or MRSA ATCC 43300
0.014-0.057 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0329043 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 43300
0.057 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
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