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MYP_153040
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Basic Information
Alyteserin-2a [G11k]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C76H139N19O21
Standard
Sequence
ILGKLLSTAAKLLSNL
Physicochemical Analysis
1655.03 Da
10.00
1.76
1.55
0.1099
1.06
0.58
0.33
5.49
183.12
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
655.64
-4.84
23.0
23.0
58.0
116.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0235981 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0253216 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0258635 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: A549
28 μM
LC50
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0274514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
32 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0277349 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 700603
64 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
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