Peptide Database

Peptide NameMidkine-A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length122 amino acids

Chemical FormulaC572H937N171O178S10

DescriptionStandard

        AAKNKKEKGKKGASDCTEWTWGSCIPNSKDCGAGTREGTCKEETRKLKCKIPCNWKKAFGADCKYKFENWGECNATTGQKVRSGTLKKALYNADCQQTVEATKPCSLKTKSKSKGKKGKGKE
    

Molecular Weight13378.25 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)16.70

Net Charge (pH 7.4) 16.30

Charge Density (pH 7.0) 0.1369

GRAVY Index-1.18

Hydrophobic Moment 0.52

Boman Index-0.30

Instability Index2.88

Aliphatic Index 32.13

Aromaticity 0.0656

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5786.76

LogP -72.71

H-bond Donors 212.0

H-bond Acceptors 205.0

Rotatable Bonds 474.0

Heavy Atoms 931.0

Ring Count 15.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201526 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStreptococcus pyogenes strain AP1

RECORD: Rec_0334630 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa strain 27-1

RECORD: Rec_0369891 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli strain 37.4

RECORD: Rec_0387798 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus strain 5120