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MYP_152999
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Basic Information
OXM(1-37) (Oxyntomodulin)
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C192H295N61O60S
Standard
Sequence
HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIA
Physicochemical Analysis
4449.83 Da
9.98
2.85
2.59
0.0769
-1.24
0.66
-0.33
73.43
44.86
0.1351
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2050.63
-25.71
73.0
65.0
149.0
314.0
7.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043506 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Oxyntomodulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anti-apetizer
MS
P800 plasma, in vitro; >259200 s
PaperDegradation and Stabilization of Peptide Hormones in Human Blood Specimens PMID26222180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26222180/
RECORD: Rec_0079142 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Oxyntomodulin
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation Feeding regulator
Experimental: 1.7 hours; /6120 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxyntomodulin (Rattus norvegicus): PMID 7937770##19602537 PMID7937770;19602537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7937770/
RECORD: Rec_0138574 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Oxyntomodulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antidiabetic
mGCGR
0.0062 μM
RP-HPLC and ESI-MS
Mouse plasma (Subcutaneous injection), in vivo; ~36000 s
PMID19602537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19602537/
RECORD: Rec_0196979 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
RECORD: Rec_0203892 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Glucagon
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID7937770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7937770/
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