Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length182 amino acids

Chemical FormulaC885H1384N236O241S5

DescriptionStandard

        PVELPVAQEPMLLVAVTDFVANSAAFAYFTAGALRRNISSATVLQRFPLQLKTKSFGIFTPQLQERFPDQPMELQVWARQQPLFSCHPDAVHGALFGSAEAFVLLPNGTRVPAFLLDIPCPLHPLGTGEPCPLHPLGAGSGVPGGAVAPVPGSGLPVPQVQRLETLLNLGLRLFGVPRANSE
    

Molecular Weight19346.22 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-0.69

Net Charge (pH 7.4) -1.02

Charge Density (pH 7.0) -0.0038

GRAVY Index0.23

Hydrophobic Moment 0.59

Boman Index0.20

Instability Index49.40

Aliphatic Index 98.08

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7363.88

LogP -79.41

H-bond Donors 244.0

H-bond Acceptors 249.0

Rotatable Bonds 596.0

Heavy Atoms 1367.0

Ring Count 42.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401750 VERIFIED: NO

Provenance & Taxonomy

OrganismEolophus roseicapilla (Galah cockatoo) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria