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MYP_152982
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Basic Information
Elotuzumab
Anticancer
Immunology ▸ Immunomodulation ▸ Immunotherapy
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
not Standard
494 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
APQPPNILLLLMDDMGWGDLGVYGEPSRETPLCSPSRAALLTGRLPIRNGFYTTNAXNLLKKAGYVSKIVGKWHLGHRPQFHPLKHGFNIPVYRDWEMVGRYYEEFPINLKTGEANLTFLYWAVDATHAPVYASKPFLGTSQRGRYGDVADNTFVFFTSDNGAALISAPEQGGSNGPFPGHVTAGQVSHQLGSIMDLFTTSLALAGLTLMDRPIFYYRGDTLMAATLGQHKAHFWTWTVTTHNLEDHTKLPLIFHLGRDPGERFPLSFEALVPAQPQLNVCNWAVMNWAPPGCEKLGKPNLDRMAAEGLLFPNFYSANAYTPQEIVGGIPDSEQLLPEDEWFGSPNCHFGPYDNKARPQIYLQEALDFIKRQARHHPFAVREIDDSIGKILELLQDLHLCGKQTTFEGGMREPALAWWPPSDRAIDGLNLLPTLLQGRNSWENFRQGIDFCPGQNVSGASAEYQEALSRITSVVQQHQCLTPPESIPKKCLWSH
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0100442 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Mus musculus [Animal]
Monoclonal antibody
9606;10090
Structure & Mods
linear multidomain protein biologic [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Anticancer Monoclonal antibody Immunotherapy
PaperPubMed-linked source references: PMID:28259300; PMID:27195659; PMID:26651519; PMID:26362528; PMID:23254906; PMID:27363832; PMID:26445358 PMID28259300;27195659;26651519;26362528;23254906;27363832;26445358 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28259300/ PatentUS2014055370
RECORD: Rec_0158740 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Enzyme
32630
Structure & Mods
linear multidomain protein biologic [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Enzyme replacement
wk 0: 7.52 minweek 22: 35.9 min
PaperPubMed-linked source references: PMID:24958960 PMID24958960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24958960/