Peptide Database

Peptide NameCecropin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC175H299N53O42

DescriptionStandard

        RWKVFKKIEKVGRNVRDGIIKAGPAIGVLGQAKAL
    

Molecular Weight3817.58 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1931

GRAVY Index-0.09

Hydrophobic Moment 0.91

Boman Index-0.03

Instability Index28.81

Aliphatic Index 111.43

Aromaticity 0.0571

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1562.32

LogP -11.46

H-bond Donors 55.0

H-bond Acceptors 49.0

Rotatable Bonds 134.0

Heavy Atoms 270.0

Ring Count 4.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270354 VERIFIED: YES

Provenance & Taxonomy

OrganismSpodoptera litura [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0351885 VERIFIED: NO