Peptide Database

Peptide NameHPRP-A1-GG-iRGD

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC140H219N39O33S2

DescriptionStandard

        FKKLKKLFSKLWNWKGGCRGDKGPDC
    

Molecular Weight3040.61 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)5.74

Net Charge (pH 7.4) 5.49

Charge Density (pH 7.0) 0.2206

GRAVY Index-1.00

Hydrophobic Moment 0.77

Boman Index-0.23

Instability Index-10.58

Aliphatic Index 45.00

Aromaticity 0.1538

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1195.57

LogP -8.54

H-bond Donors 44.0

H-bond Acceptors 41.0

Rotatable Bonds 105.0

Heavy Atoms 214.0

Ring Count 7.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0309821 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman red blood cells

Activity125 μM

MethodMHC

RECORD: Rec_0363052 VERIFIED: YES