MYP_152924
IBP-CP24
Standard
37 amino acids
C210H317N49O61S3
Standard
DCAWHLGELVWCTMTWEEWDKKIEEYTKKIEELIKKS
4600.25 Da
4.91
-3.16
-3.46
-0.0853
-0.77
0.69
-0.07
52.71
73.78
0.1351
23490.00
23615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1795.73
-8.23
65.0
62.0
156.0
323.0
10.0
36.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0432502
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-HIV-1
Fusion inhibition
HIV-1 NL4-3 V38A/N42T
3.6±1.2 nM
IC50 (viral infection inhibition)
RECORD: Rec_0432503
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
In vivo anti-HIV-1
humanized mice challenged with HIV-1 JR-CSF
protected qualitative
prophylactic challenge experiment
RECORD: Rec_0432504
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
In vivo anti-HIV-1 treatment
chronically HIV-1-infected humanized mice treated with IBP-CP24 plus neutralizing antibody
decreased plasma viremia qualitative
in-vivo combination-treatment viral-load experiment
RECORD: Rec_0432505
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Pharmacokinetics
rhesus macaque plasma
46.11 h
plasma half-life by sandwich ELISA
Showing 4 records · Page 3 of 3