Peptide Database

Peptide NameCathelicidin-1 (1-15), CATH-1 (1-15), Fowlicidin-1 (1-15)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC85H148N26O17

DescriptionStandard

        RVKRVWPLVIRTVIA
    

Molecular Weight1806.25 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2506

GRAVY Index0.72

Hydrophobic Moment 0.78

Boman Index0.04

Instability Index29.15

Aliphatic Index 162.00

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 709.67

LogP -2.50

H-bond Donors 27.0

H-bond Acceptors 21.0

Rotatable Bonds 57.0

Heavy Atoms 128.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010710 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetMadin-Darby canine kidney cells 50% Cell death at >443 microM

Activity443 μM

MethodHemolysis

RECORD: Rec_0202144 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity6.9 μM

MethodMIC

RECORD: Rec_0297082 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetListeria monocytogenes ATCC 19115

Activity13.08 μM

MethodMIC

RECORD: Rec_0396036 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetSalmonella enterica subsp. enterica serovar Typhimurium ATCC 14028

Activity3.5 μM

MethodMIC

RECORD: Rec_0404489 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 25923

Activity13.08 μM

MethodMIC