Peptide Database

Peptide NameHongotoxin-1, HgTX1

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC181H299N53O49S7

DescriptionStandard

        TVIDVKCTSPKQCLPPCKAQFGIRAGAKCMNGKCKCYPH
    

Molecular Weight4226.09 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.42

Net Charge (pH 7.4) 5.08

Charge Density (pH 7.0) 0.1390

GRAVY Index-0.25

Hydrophobic Moment 0.56

Boman Index-0.05

Instability Index44.85

Aliphatic Index 52.56

Aromaticity 0.0513

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1628.15

LogP -17.59

H-bond Donors 60.0

H-bond Acceptors 63.0

Rotatable Bonds 137.0

Heavy Atoms 290.0

Ring Count 7.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265814 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides limbatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

TargetKv1

RECORD: Rec_0336776 VERIFIED: YES